Job Description

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Research Officer - Vascular Immunology

Advertiser: The Heart Research Institute LtdMore jobs from this company

Job Information

Job Listing Date
7 May 2019
Location
Sydney, CBD, Inner West & Eastern Suburbs
Work Type
Full Time
Classification
Science & Technology, Biological & Biomedical Sciences

Research Officer - Vascular Immunology

  • Oustanding opportunity to work in a world class research and education precinct
  • Dynamic and successful collaborative research program

An exciting opportunity exists to join a successful research group as part of a partnership between The Heart Research Institute and the University of Sydney's Charles Perkins Centre, a world class research and education precinct that is addressing the global epidemic of obesity, diabetes and cardiovascular disease – the leading causes of mortality in Australia. 

The impact of cardiovascular disease, especially high blood pressure, in women during pregnancy and beyond, has been a focus of the institute and the vascular immunology research group since 2002.

THE HEART RESEARCH INSTITUTE (HRI) is a centre of excellence in cardiovascular medical research, affiliated with the Royal Prince Alfred Hospital and the University of Sydney located in Newtown, Sydney. The primary focus of the Institute is to make fundamental discoveries in cardiovascular research that will advance the detection, prevention and treatment of cardiovascular disease.

THE CHARLES PERKINS CENTRE is facilitating world-class research; the translation of knowledge into practical solutions; the development of innovative, cross-disciplinary teaching programs to inspire the next generation of researchers; and forging new research partnerships within and beyond the University to enable the centre to deliver unique insights and results. This ambitious mission is underpinned by two key components:

  • An academic program that covers research and teaching
  • A state-of-the-art world-class building completed in 2014

By bringing together our best minds from across the academic spectrum through cross-disciplinary collaboration, the partnership between The Heart Research Institute and the Charles Perkins Centre is addressing the global crisis in obesity, diabetes and cardiovascular disease. For more information on the Charles Perkins Centre visit: http://sydney.edu.au/perkins/

The position: Interested applicants will be joining a dynamic research program in the Vascular Immunology Research Group of HRI, headed by Professor Annemarie Hennessy (Renal and Obstetric Physician Scientist, HRI) involving collaborative research with local and international research groups, including Professor Angela Makris (Director of Women's Health Innovation and Translation Unit, Liverpool Hospital, and HRI ) and Professor Ananth Karumanchi (Medallion Chair in Vascular Biology, Cedars-Sinai, California USA).

The research program is aimed at investigating novel therapeutic treatments for preeclampsia, or high blood pressure in pregnancy, in the context of placental and vascular disease in high risk women. More specifically, we will be investigating the mechanism of action and the efficacy of agents designed to target placental toxins; treatments as novel anti-angiogenic targets. A variety of inflammatory and biochemical assays will be used in vitro on human and animal model blood samples, and in vivo, using multiple models of preeclampsia.

The program incorporates a substantial multidisciplinary research effort involving animal handling, live cell imaging, molecular techniques, protein chemistry and cell biology.

Essential criteria – you will have:

  • A PhD in a relevant area of medical science
  • Experience in performing biochemical assays
  • Experience in cell biology
  • Experience in animal models and animal handling
  • Confocal microscopy experience
  • Enthusiasm about drug development/discovery
  • A strong interest and commitment in translational research and producing good quality publications
  • High levels of motivation and the capacity for independent work
  • A track record of being team focused
  • Good interpersonal, written, and oral communication skills, including contributing to grant writing
  • Desirable criteria – you will have:

  • Experience in cell harvesting and cell culture
  • Experience in models of inflammation
  • Basic knowledge of pharmacokinetic/pharmacodynamic modelling

Position requirements: In addition to the listed criteria, the successful candidate will be expected to contribute to the research program by performing a range of research related tasks which may include the following:

  • Assist in the conduct and design of experiments
  • Assist in the general supervision of students in the laboratory
  • Assist in the preparation of documents (for grant applications, research/conference papers, ethics applications)
  • Provide administrative and financial management support for research projects and programs including the maintenance of electronic data bases and records
  • Maintain lab equipment and materials including waste disposal and ordering supplies

The position is full time, however flexible working arrangements may be negotiated.  The appointment period is for 12 months with the possibility of renewal for a maximum of 3 years (for the duration of a current NHMRC grant). You will be employed by the Heart Research Institute but will be required to work at our premises at the Charles Perkins Centre located nearby at the University of Sydney, or occasionally, at the laboratories of the relevant participating hospitals and Western Sydney University (a major partner in this work). This is an outstanding opportunity to develop skills and gain valuable experience conducting innovative research in state-of-the-art facilities.

We Offer: A competitive remuneration package, along with generous not-for-profit salary-packaging options.

How to apply: Your application should include:

  • a cover letter and detailed curriculum vitae (CV)
  • the names and full contact details of three professional referees (including email addresses)

Further information can be obtained by contacting Professor Annemarie Hennessy by email at an.hennessy@westernsydney.edu.au

Closing Date: Applications close 2nd June 2019, however applications will be assessed and shortlisted as they are received, so please apply as soon as possible.

Eligibility: To apply for this position you must have an appropriate Australian or New Zealand work visa.

Please note: Due to the volume of applications expected, only short-listed candidates may be contacted.

This is a Category A position according to the NSW Health Policy - Occupational Assessment, Screening Vaccination Against Specified Infectious Diseases. The successful applicant will be required to provide evidence of protection against the infectious diseases specified, at their own cost, prior to appointment.

The Heart Research Institute supports Equal Employment Opportunity. We value diversity and encourage applications from women, Aboriginal and Torres Strait Islanders, people with disability, LGBTQI individuals and applicants of diverse cultures and ages.

 


Email: Please click the 'Apply Now' button below.

An exciting opportunity exists to join a successful research group as part of a partnership between The Heart Research Institute and the University of Sydney's Charles Perkins Centre, a world class research and education precinct that is addressing the global epidemic of obesity, diabetes and cardiovascular disease – the leading causes of mortality in Australia. 

The impact of cardiovascular disease, especially high blood pressure, in women during pregnancy and beyond, has been a focus of the institute and the vascular immunology research group since 2002.

THE HEART RESEARCH INSTITUTE (HRI) is a centre of excellence in cardiovascular medical research, affiliated with the Royal Prince Alfred Hospital and the University of Sydney located in Newtown, Sydney. The primary focus of the Institute is to make fundamental discoveries in cardiovascular research that will advance the detection, prevention and treatment of cardiovascular disease.

THE CHARLES PERKINS CENTRE is facilitating world-class research; the translation of knowledge into practical solutions; the development of innovative, cross-disciplinary teaching programs to inspire the next generation of researchers; and forging new research partnerships within and beyond the University to enable the centre to deliver unique insights and results. This ambitious mission is underpinned by two key components:

  • An academic program that covers research and teaching
  • A state-of-the-art world-class building completed in 2014

By bringing together our best minds from across the academic spectrum through cross-disciplinary collaboration, the partnership between The Heart Research Institute and the Charles Perkins Centre is addressing the global crisis in obesity, diabetes and cardiovascular disease. For more information on the Charles Perkins Centre visit: http://sydney.edu.au/perkins/

The position: Interested applicants will be joining a dynamic research program in the Vascular Immunology Research Group of HRI, headed by Professor Annemarie Hennessy (Renal and Obstetric Physician Scientist, HRI) involving collaborative research with local and international research groups, including Professor Angela Makris (Director of Women's Health Innovation and Translation Unit, Liverpool Hospital, and HRI ) and Professor Ananth Karumanchi (Medallion Chair in Vascular Biology, Cedars-Sinai, California USA).

The research program is aimed at investigating novel therapeutic treatments for preeclampsia, or high blood pressure in pregnancy, in the context of placental and vascular disease in high risk women. More specifically, we will be investigating the mechanism of action and the efficacy of agents designed to target placental toxins; treatments as novel anti-angiogenic targets. A variety of inflammatory and biochemical assays will be used in vitro on human and animal model blood samples, and in vivo, using multiple models of preeclampsia.

The program incorporates a substantial multidisciplinary research effort involving animal handling, live cell imaging, molecular techniques, protein chemistry and cell biology.

Essential criteria – you will have:

  • A PhD in a relevant area of medical science
  • Experience in performing biochemical assays
  • Experience in cell biology
  • Experience in animal models and animal handling
  • Confocal microscopy experience
  • Enthusiasm about drug development/discovery
  • A strong interest and commitment in translational research and producing good quality publications
  • High levels of motivation and the capacity for independent work
  • A track record of being team focused
  • Good interpersonal, written, and oral communication skills, including contributing to grant writing
  • Desirable criteria – you will have:

  • Experience in cell harvesting and cell culture
  • Experience in models of inflammation
  • Basic knowledge of pharmacokinetic/pharmacodynamic modelling

Position requirements: In addition to the listed criteria, the successful candidate will be expected to contribute to the research program by performing a range of research related tasks which may include the following:

  • Assist in the conduct and design of experiments
  • Assist in the general supervision of students in the laboratory
  • Assist in the preparation of documents (for grant applications, research/conference papers, ethics applications)
  • Provide administrative and financial management support for research projects and programs including the maintenance of electronic data bases and records
  • Maintain lab equipment and materials including waste disposal and ordering supplies

The position is full time, however flexible working arrangements may be negotiated.  The appointment period is for 12 months with the possibility of renewal for a maximum of 3 years (for the duration of a current NHMRC grant). You will be employed by the Heart Research Institute but will be required to work at our premises at the Charles Perkins Centre located nearby at the University of Sydney, or occasionally, at the laboratories of the relevant participating hospitals and Western Sydney University (a major partner in this work). This is an outstanding opportunity to develop skills and gain valuable experience conducting innovative research in state-of-the-art facilities.

We Offer: A competitive remuneration package, along with generous not-for-profit salary-packaging options.

How to apply: Your application should include:

  • a cover letter and detailed curriculum vitae (CV)
  • the names and full contact details of three professional referees (including email addresses)

Further information can be obtained by contacting Professor Annemarie Hennessy by email at an.hennessy@westernsydney.edu.au

Closing Date: Applications close 2nd June 2019, however applications will be assessed and shortlisted as they are received, so please apply as soon as possible.

Eligibility: To apply for this position you must have an appropriate Australian or New Zealand work visa.

Please note: Due to the volume of applications expected, only short-listed candidates may be contacted.

This is a Category A position according to the NSW Health Policy - Occupational Assessment, Screening Vaccination Against Specified Infectious Diseases. The successful applicant will be required to provide evidence of protection against the infectious diseases specified, at their own cost, prior to appointment.

The Heart Research Institute supports Equal Employment Opportunity. We value diversity and encourage applications from women, Aboriginal and Torres Strait Islanders, people with disability, LGBTQI individuals and applicants of diverse cultures and ages.

 

The application form will include these questions:
  • Which of the following statements best describes your right to work in Australia?
  • What's your highest level of education?
  • How much notice are you required to give your current employer?
  • What's your expected annual base salary?

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